A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor

Canini Laetitia; Lemenuel-Diot Annabelle; Brennan Barbara J.; Smith Patrick F.; Perelson Alan S.

首页> 外文期刊>Antiviral therapy >A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor

【24h】

A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor

机译：一种药代动力学/病毒动力学模型，评价慢性HCV感染与非核苷聚合酶抑制剂的治疗

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Background: Viral kinetic models have proven useful in characterizing treatment effectiveness during HCV therapy with interferon (IFN) as well as with direct-acting antivirals (DAAs).

机译：背景：病毒动力学模型已经证明，在具有干扰素（IFN）以及直接作用抗病毒（DAAS）期间，有用的病毒动力学模型可用于表征治疗效果。

著录项

来源
《Antiviral therapy》 |2018年第4期|共9页
作者
Canini Laetitia; Lemenuel-Diot Annabelle; Brennan Barbara J.; Smith Patrick F.; Perelson Alan S.;
展开▼
作者单位

Los Alamos Natl Lab Theoret Biol &

Biophys Los Alamos NM 87545 USA;

Roche Pharma Dev Methodol &

Innovat Dept Basel Switzerland;

Roche Clin Pharmacol Pharma Res &

Early Dev Nutley NJ USA;

d3 Med Parsippany NJ USA;

Los Alamos Natl Lab Theoret Biol &

Biophys Los Alamos NM 87545 USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词

相似文献

外文文献
中文文献
专利

1. A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor [J] . Canini Laetitia, Lemenuel-Diot Annabelle, Brennan Barbara J., Antiviral therapy . 2018,第4期

机译：一种药代动力学/病毒动力学模型，评价慢性HCV感染与非核苷聚合酶抑制剂的治疗
2. Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections. [J] . Beaulieu PL Current opinion in investigational drugs . 2007,第8期

机译：HCV NS5B聚合酶的非核苷抑制剂：在发现和开发用于治疗HCV感染的新型药物方面的进展。
3. A pharmacokinetic/viral kinetic model to evaluate the treatment effectiveness of danoprevir against chronic HCV [J] . Canini Laetitia, Chatterjee Anushree, Guedj Jeremie, Antiviral therapy . 2015,第5期

机译：药代动力学/病毒动力学模型，用于评估达诺普韦对慢性HCV的治疗效果
4. Cluster analysis in assessing the interdependencies of clinical and morphological parameters of patients with mixed infections (pulmonary tuberculosis, chronic viral hepatitis, HIV infection) and heroin addiction [C] . Pigul Evgeniia Yu, Filimonova Galina F., Tokin Ivan B., 2015 International Conference "Stability and Control Processes" in Memory of V.I. Zubov . 2015

机译：聚类分析评估混合感染（肺结核，慢性病毒性肝炎，HIV感染）和海洛因成瘾患者临床和形态学参数之间的相互依赖性
5. Mathematical Modeling as a Tool to Elucidate HCV Infection Kinetics and Treatment Response [D] . Sansone, Natasha D. 2017

机译：数学模型作为阐明HCV感染动力学和治疗反应的工具
6. A pharmacokinetic/viral kinetic model to evaluate treatment of chronic hepatitis C virus infection with a non-nucleoside polymerase inhibitor [O] . Laetitia Canini, Annabelle Lemenuel-Diot, Barbara J. Brennan, -1

机译：用药代动力学/病毒动力学模型评估非核苷聚合酶抑制剂对慢性丙型肝炎病毒感染的治疗
7. Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model [O] . Biswas, S., Sukla, S., Goldner, T., 2014

机译：在鼠单纯疱疹病毒1感染模型中治疗野生型或抗吡咯韦韦的病毒感染后，解旋酶-引发酶抑制剂吡替韦的药代动力学-药效学
8. Compounds, Methods and Compositions Useful for the Treatment of Bovine Viral Diarrhea Virus (BVDV) Infection and Hepatitis C Virus (HCV) Infection. [R] . Dykstra, C. C., Givens, M. D., Stringfellow, D. A., 2005

机译：可用于治疗牛病毒性腹泻病毒（BVDV）感染和丙型肝炎病毒（HCV）感染的化合物，方法和组合物。

A pharmacokinetic/viral kinetic model to evaluate treatment of chronic HCV infection with a non-nucleoside polymerase inhibitor

摘要

著录项

相似文献

相关主题

期刊订阅