STUDIES ON THE PERMEABILITY OF THE BLOOD-TESTIS BARRIER IN STAINLESS STEEL-ADMINISTERED MICE

Pereira ML

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STUDIES ON THE PERMEABILITY OF THE BLOOD-TESTIS BARRIER IN STAINLESS STEEL-ADMINISTERED MICE

机译：钢制小鼠的血-铁血屏障通透性研究

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Previous trials performed in our laboratory have demonstrated that stainless steel corrosion products induced morphological changes in mice seminiferous cells. In this study the functional nature of the blood-testis barrier was investigated, in view of the extesive use of this metallic alloy in orthopaedic surgery. The uptake of horseradish peroxidase by the seminiferous tubules was used as a tracer method being exposed in vitro for different periods of time and observed at the ultrastructural level. Both boundary cells as well as Sertoli cells of experimental group absorbed the tracer, as manifested by vesicles and vacuoles filled with the reaction product, evidencing its role within the testis. Germ cells were also able in the uptake of this macromolecule. However, the tracer did not spread into the junctional complexes between neighboring Sertoli cells, at any interval of time used in this study, demonstrating the functional integrity of this barrier.

机译：在我们实验室中进行的先前试验已经证明，不锈钢腐蚀产物会诱导小鼠生精细胞的形态变化。在这项研究中，考虑到这种金属合金在整形外科手术中的广泛使用，研究了血液-睾丸屏障的功能性质。曲细精管吸收辣根过氧化物酶被用作示踪剂方法，在体外暴露了不同的时间，并在超微结构水平上观察到。实验组的边界细胞和支持细胞均吸收了示踪剂，示为囊泡和液泡中充满了反应产物，证明了其在睾丸中的作用。生殖细胞也能够摄取这种大分子。但是，在本研究中使用的任何时间间隔，示踪剂都不会扩散到相邻Sertoli细胞之间的连接复合物中，这证明了该屏障的功能完整性。

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《Cell biology international.》 |1995年第7期|共6页
作者
Pereira ML;
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正文语种 eng
中图分类细胞生物学;
关键词
Sertoli cell junctions; Seminiferous tubule; Freeze fracture; Rat;

机译：睾丸支持细胞交界;小叶小管;冷冻断裂;大鼠;

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专利

1. STUDIES ON THE PERMEABILITY OF THE BLOOD-TESTIS BARRIER IN STAINLESS STEEL-ADMINISTERED MICE [J] . Pereira ML Cell biology international. . 1995,第7期

机译：钢制小鼠的血-铁血屏障通透性研究
2. Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics? [J] . Li MW, Mruk DD, Lee WM The international journal of biochemistry and cell biology . 2009,第11期

机译：双酚A在体外破坏血液-睾丸屏障的完整性：这是研究血液-睾丸屏障动力学的合适模型吗？
3. Super Antibiotics, Part II. Hyperforin, Mass Spectroscopy (MS) and Gas Chromatography-Mass Spectrometry (GC-MS), Evidence of Permeability of the Blood-Testis Barrier (BTB) and the Blood-Brain Barrier (BBB) to Hyperforin [J] . Ilia Brondz International Journal of Analytical Mass Spectrometry and Chromatography . 2016,第4期

机译：超级抗生素，第二部分。 Hyperforin，质谱（MS）和气相色谱-质谱（GC-MS），血睾丸屏障（BTB）和血脑屏障（BBB）对Hyperforin的渗透性证据
4. Reactive and hydraulic behavior of Permeable Reactive Barriers constituted by Fe~0 and granular mixtures of Fe~0/pumice [C] . Stefania Bilardi, Domenico Ielo, Nicola Moraci Italian Conference on Researchers in Geotechnical Engineering . 2016

机译：由Fe〜0和Fe〜0 /浮石的Fe〜0和颗粒混合物构成的可渗透反应屏障的反应性和液压行为
5. The TH2 bias in CNS immune privilege: Induction of humoral, cellular, and cytokine immune responses to soluble protein antigen administered into the cerebrospinal fluid of mice with normal blood brain barrier permeability. [D] . Park, Joel Thomas, II. 2003

机译：在中枢神经系统免疫特权中的TH2偏倚：诱导对可溶性蛋白抗原的体液，细胞和细胞因子免疫反应，这些抗原被注入具有正常血脑屏障通透性的小鼠的脑脊液中。
6. Disruption of the blood-testis barrier integrity by bisphenol A in vitro: Is this a suitable model for studying blood-testis barrier dynamics? [O] . Michelle W. M. Li, Dolores D. Mruk, Will M. Lee, -1

机译：通过双酚A体外破坏血液睾丸屏障完整性：这是研究血液睾丸屏障动态的合适模型吗？
7. Disruption of the blood-testis barrier integrity by bisphenol A in vitro: Is this a suitable model for studying blood-testis barrier dynamics? [O] . Lee WM, Cheng CY, Li MWM, 2009

机译：双酚a体外破坏血睾屏障完整性：这是研究血睾屏障动力学的合适模型吗？

STUDIES ON THE PERMEABILITY OF THE BLOOD-TESTIS BARRIER IN STAINLESS STEEL-ADMINISTERED MICE

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