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首页> 外文期刊>Frontiers in neuroendocrinology >Neuroendocrinology of song behavior and avian brain plasticity: multiple sites of action of sex steroid hormones.
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Neuroendocrinology of song behavior and avian brain plasticity: multiple sites of action of sex steroid hormones.

机译:歌曲行为和禽类大脑可塑性的神经内分泌学:性类固醇激素的多个作用部位。

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摘要

Seasonal changes in the brain of songbirds are one of the most dramatic examples of naturally occurring neuroplasticity that have been described in any vertebrate species. In males of temperate-zone songbird species, the volumes of several telencephalic nuclei that control song behavior are significantly larger in the spring than in the fall. These increases in volume are correlated with high rates of singing and high concentrations of testosterone in the plasma. Several song nuclei express either androgen receptors or estrogen receptors, therefore it is possible that testosterone acting via estrogenic or androgenic metabolites regulates song behavior by seasonally modulating the morphology of these song control nuclei. However, the causal links among these variables have not been established. Dissociations among high concentrations of testosterone, enlarged song nuclei, and high rates of singing behavior have been observed. Singing behavior itself can promote cellular changes associated with increases in the volume of the song control nuclei. Also, testosterone may stimulate song behavior by acting in brain regions outside of the song control system such as in the preoptic area or in catecholamine cell groups in the brainstem. Thus testosterone effects on neuroplasticity in the song system may be indirect in that behavioral activity stimulated by testosterone acting in sites that promote male sexual behavior could in turn promote morphological changes in the song system.
机译:鸣禽的大脑中的季节性变化是任何脊椎动物物种中描述的自然发生的神经可塑性的最显着例子之一。在温带地区的鸣禽物种的雄性中,春季控制春季行为的几个远脑核的数量明显大于秋季。这些音量的增加与血浆中高歌唱率和高浓度睾丸激素有关。几个歌曲核表达雄激素受体或雌激素受体,因此通过雌激素或雄激素代谢物起作用的睾丸激素有可能通过季节性调节这些歌曲控制核的形态来调节歌曲行为。但是,这些变量之间的因果关系尚未建立。已经观察到高浓度的睾丸激素,增大的歌核和较高的歌唱行为之间的分离。歌唱行为本身可以促进与歌曲控制核体积增加相关的细胞变化。同样,睾丸激素可通过在歌曲控制系统外部的大脑区域(例如在视神经前部区域或脑干中的儿茶酚胺细胞群中)起作用来刺激歌曲行为。因此,睾丸激素对歌曲系统中神经可塑性的影响可能是间接的,因为睾丸激素在促进男性性行为的部位起作用而刺激的行为活动反过来又可以促进歌曲系统中的形态变化。

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