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首页> 外文期刊>Frontiers in neuroendocrinology >Melatonin in psychiatric disorders: a review on the melatonin involvement in psychiatry.
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Melatonin in psychiatric disorders: a review on the melatonin involvement in psychiatry.

机译：精神疾病中的褪黑素：关于褪黑素参与精神病学的综述。

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摘要

In normal subjects, the secretion of melatonin, the pineal hormone that regulates the rhythm of many functions, exhibits a circadian pattern synchronized with the day-night cycle. An alteration of this secretory pattern has been found in various psychiatric disorders (seasonal affective disorder, bipolar disorder, unipolar depression, bulimia, anorexia, schizophrenia, panic disorder, obsessive compulsive disorder). At present, it is not known if such alterations have an etiological role or are secondary to the dysfunctions underlying the different disorders. In addition, we do not know if the involvement of melatonin in several disorders has the same significance in the pathophysiology of each disorder. An understanding of the role of the pineal hormone and of its alterations in psychiatric diseases could help to identify the biological mechanisms underlying such disorders.
机译：在正常受试者中，褪黑激素（一种调节许多功能的节律的松果激素）的分泌表现出与昼夜周期同步的昼夜节律。在各种精神病（季节性情感障碍，双相情感障碍，单相抑郁症，贪食症，厌食症，精神分裂症，恐慌症，强迫症）中都发现了这种分泌方式的改变。目前，尚不清楚这种改变是否具有病因学作用或者是继发于不同疾病的功能障碍所致。另外，我们不知道褪黑激素参与多种疾病在每种疾病的病理生理学中是否具有相同的意义。了解松果体激素及其变化在精神疾病中的作用可能有助于确定这类疾病的生物学机制。

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