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首页> 外文期刊>Scandinavian journal of clinical and laboratory investigation. >Establishing cut-offs for urine erythrocyte and leukocyte dipstick tests
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Establishing cut-offs for urine erythrocyte and leukocyte dipstick tests

机译：为尿红细胞和白细胞减少仪测试建立截止

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Urine erythrocyte (Ery) and leukocyte (Leu) dipstick tests are essential for detecting microhematuria and urinary tract infection. Currently, there is no suggestion for establishing the cut-off limits in an ordinal scale test. This study aimed to establish the cut-off limits for urine Ery and Leu dipstick tests via probit regression. From 1 January 2016 to 30 June 2016, laboratory data were collected from patients at one teaching hospital whose specimen had analytical results from both a urine dipstick test and an automated urine particle analyzer. Probit regression was used to estimate the probability of positive urine dipstick results as a function of log-transformed urine Ery and Leu concentrations. Based on the analysis of 22,122 specimens, the estimated concentration that yields 50% positive results (C-50) of the Ery weak+, 1+, 2+, 3+, and 4+dipstick results were 14.6, 40.4, 51.6, 136.3 and 219.0 x 10(6)/L, respectively. The estimated C-50 of the Leu 1+, 2+ and 3+dipstick results were 22.7, 67.9 and 283.9 x 10(6)/L, respectively. The estimated values were different from arbitrary concentrations provided for each dipstick category by the manufacturer. If a quantitative comparison method/procedure is available, the cut-off limits of an ordinal scale test can be established using probit regression. Each laboratory should investigate the transferability of the arbitrary concentrations provided by the manufacturer, and if necessary, determine its own cut-off limits of urine Ery and Leu dipstick tests.
机译：尿红细胞（葡萄酒）和白细胞（Leu）Dipstick测试对于检测微藻和泌尿道感染是必不可少的。目前，没有建议在序数测试中建立截止限制。本研究旨在通过探测回归来建立尿液和黎氏Dipstick测试的截止限制。从2016年1月1日至2016年6月30日，从一个教学医院收集了实验室数据，其标本具有来自Dipstick测试和自动尿液颗粒分析仪的分析结果。概率回归用于估计正尿液降低结果的概率作为对数转化的尿液和雷浓度的函数。基于22,122标本的分析，产生50％阳性结果（C-50）的估计浓度（C-50）的弱+，1+，2+，3+和4 + Dipstick结果为14.6,40.4,51.6,136.3和分别为219.0 x 10（6）/ L.估计的Leu1，2+和3 + Dipstick结果的C-50分别为22.7,67.9和283.9×10（6）/ L.估计值与制造商为每个Dipstick类别提供的任意浓度不同。如果可以使用定量比较方法/程序，可以使用概率回归建立序列测量测试的截止限制。每个实验室都应调查制造商提供的任意浓度的可转移性，以及必要时确定其自身的尿液尿液和Leu Dipstick测试的截止限制。

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