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首页> 外文期刊>International Journal of Nutrition and Food Sciences >Milk consumption is not affected by C/T-13910 single nucleotide polymorphism in a Tajik population in a southern region of Uzbekistan
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Milk consumption is not affected by C/T-13910 single nucleotide polymorphism in a Tajik population in a southern region of Uzbekistan

机译：乌兹别克斯坦南部塔吉克族人群的牛奶消费不受C / T-13910单核苷酸多态性的影响

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Objective: To determine the prevalence of adult-type hypolactasia in the Tajik population living in the south of Uzbekistan by genotyping of allelic variants C/T-13910 and identifying their tolerance to milk. Methods: 100 ethnic Tajik adults were examined for C/T-13910 single nucleotide polymorphisms using polymerase chain reaction/restriction fragment length polymorphism. Milk tolerance was analyzed by a questionnaire developed to assess dyspepsia after milk and dairy consumption. Results: A genetic marker of hypolactasia - C/C-13910 genotype was detected in 83% of the adult Tajik population. However, despite the high prevalence of lactose intolerance in the Tajik population, the majority consume between 100-200 ml of milk per day. Conclusion: The Tajik population is characterized by a high prevalence of hypolactasia. Milk consumption is not affected by the determined genotypes since people of Tajik ethnicity consume milk in small quantities.
机译：目的：通过对等位基因变体C / T-13910进行基因分型并鉴定其对牛奶的耐受性，确定生活在乌兹别克斯坦南部塔吉克人群中成人型泌乳不足的患病率。方法：使用聚合酶链反应/限制性片段长度多态性，对100名塔吉克族成年人的C / T-13910单核苷酸多态性进行了检查。牛奶耐受性通过问卷调查进行分析，以评估食用牛奶和乳制品后的消化不良。结果：83％的塔吉克族成年人中检出了泌乳不足的遗传标记-C / C-13910基因型。然而，尽管塔吉克族人群中乳糖不耐症的患病率很高，但大多数人每天仍消耗100-200毫升牛奶。结论：塔吉克族人群具有高度的泌乳失调特征。牛奶消费不受确定的基因型的影响，因为塔吉克族人食用少量牛奶。

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