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Involvement of miR-126 in autoimmune disorders

机译:miR-126参与自身免疫性疾病

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摘要

BackgroundMicro-RNA represent a great family of small non-condign ribonucleic acid molecules; in particular microRNA-126 is an important member of this family and is expressed in many human cells such as cardiomyocytes, endothelial and lung cells. Some studies have shown the implication of miR-126 in cancer, but recently significant progresses have also been made in determining the role of miR-126 regulating immune-related diseases; probably, in a near future, they could potentially serve as diagnostic biomarkers or therapeutic targets.
机译:背景Micro-RNA代表了一个巨大的非concondign核糖核酸小分子家族;特别是microRNA-126是该家族的重要成员,并在许多人类细胞中表达,例如心肌细胞,内皮细胞和肺细胞。一些研究显示了miR-126在癌症中的意义,但最近在确定miR-126调节免疫相关疾病的作用方面也取得了重大进展。可能在不久的将来,它们可能会用作诊断生物标志物或治疗靶标。

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