首页> 外文会议>International Conference on Physical-Technical Problems of Nuclear Science, Energy Generation and Power Industry >Possibility of Using ~(99m)Tc-labeled Macro-Aggregates of Serum Albumin and Diethylene Triamine Pentaacetic Acid in the Assessment Lung Ventilation and Perfusion in Patients with Chronic Obstructive Pulmonary Disease and Coronary Artery Disease
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Possibility of Using ~(99m)Tc-labeled Macro-Aggregates of Serum Albumin and Diethylene Triamine Pentaacetic Acid in the Assessment Lung Ventilation and Perfusion in Patients with Chronic Obstructive Pulmonary Disease and Coronary Artery Disease

机译:在慢性阻塞性肺病和冠状动脉疾病患者的评估肺气通风和灌注中使用〜(99m)的血清白蛋白和二亚乙基三胺五乙酸的宏观聚集体的可能性

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Basic scintigraphy data reflecting into lung microcirculation and ventilation were studied at 12 patients with chronic obstructive pulmonary disease (COPD) of I-II degree against the background of coronary artery disease (CAD). The bilateral increase in an apical-basal gradient of perfusion that signaled about redistribution of a pulmonary blood-groove in the top parts of lungs and development of pulmonary hypertension and also slowing-down of alveolar-capillary permeability (ACP) was revealed. The revealed violations indicate more expressed changes of pulmonary microcirculation and ventilation at patients with COPD in combination with CAD and promote timely pharmacotherapy correction of the specified combined disease. Pulmonary ventilation/perfusion scintigraphy with ~(99m)Tc-labeled macro-aggregates of serum albumin (MAA) and diethylene triamine pentaacetic acid (DTPA) acid have all necessary properties for receiving high-quality lung scan.
机译:在冠状动脉疾病背景(CAD)的背景下,研究了反映肺微循环和通风的基本闪烁数据。(CAD)的慢性阻塞性肺病(COPD)。揭示了发出关于灌注的顶部基础梯度的双侧增加,所述灌注的灌注型肺血齿肺血齿的再分布以及肺动脉高压的发育以及肺泡毛细血管渗透率(ACP)的减慢速度。揭示的违规表明COPD患者的肺微循环和通风更具表达更改的肺微循环和通风,并促进了特定综合疾病的及时药物疗法校正。血清白蛋白(MAA)和二亚乙基三胺五乙酸(DTPA)酸的肺气通风/灌注闪烁刺激物与血清白蛋白(MAA)和二亚乙基三胺戊酸(DTPA)酸具有所有必要的性质,用于接受高质量的肺扫描。

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