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A Monte Carlo based radiotherapy simulator

机译:基于蒙特卡洛的放射治疗模拟器

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摘要

This paper presents a Monte Carlo based simulator of the radiotherapy treatment chain. The high energy simulation module (HESM) incorporates components for beam generation, irradiation set up, radiation transport modeling and dose distribution calculation. The beam is defined by means of particle charge, energy, direction and position. Comprehensive modeling of photon and electron interactions in the radiotherapy energy range has been pursued. A three-dimensional dose matrix is used to calculate the energy deposited by electrons and photons. The simulator was evaluated in terms of its accuracy of computation of 3D photon and electron beam dose distributions, by means of comparison to reported Monte Carlo studies and also to experimental data, using homogeneous and heterogeneous phantoms. The dose distribution studies demonstrated good agreement with experimental and reference data. Furthermore, the HESM has been augmented by means of an already available user-friendly GUI and a suit of modeling tools, to become a complete Monte Carlo radiotherapy simulator (MCRTS), for use in experimentation in general and specific radiotherapy applications.
机译:本文介绍了基于蒙特卡洛的放射治疗链仿真器。高能模拟模块(HESM)包含用于光束生成,辐照设置,辐射传输建模和剂量分布计算的组件。束通过粒子电荷,能量,方向和位置来定义。已经进行了在放射治疗能量范围内光子和电子相互作用的综合建模。三维剂量矩阵用于计算电子和光子沉积的能量。通过与已报告的蒙特卡洛研究以及使用均质和异质体模的实验数据进行比较,对模拟器的3D光子和电子束剂量分布的计算准确性进行了评估。剂量分布研究表明与实验和参考数据吻合良好。此外,借助于已经可用的用户友好的GUI和一套建模工具,HESM得到了增强,成为了完整的蒙特卡洛放射治疗模拟器(MCRTS),可用于常规和特定放射治疗应用中的实验。

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