...
首页> 外文期刊>Asian Nursing Research >Development of a Nomogram for Carbapenem-Resistant Enterobacteriaceae Acquisition Risk Prediction Among Patients in the Intensive Care Unit of a Secondary Referral Hospital
【24h】

Development of a Nomogram for Carbapenem-Resistant Enterobacteriaceae Acquisition Risk Prediction Among Patients in the Intensive Care Unit of a Secondary Referral Hospital

机译:开发CarbapeNem抗性的NOMA图肠杆菌膜斜视>患者中的患者中的患者在二级推荐医院

获取原文
           

摘要

PurposeThis study aimed to identify the risk factors of carbapenem-resistantEnterobacteriaceae(CRE) acquisition to build a nomogram for CRE acquisition risk prediction and evaluate its performance.MethodsThis unmatched case-control study included 352 adult patients (55 patients and 297 controls) admitted to the intensive care unit (ICU) of a 453-bed secondary referral hospital between January 1, 2018, and September 31, 2019, in Busan, South Korea. The nomogram was built with the identified risk factors using multiple logistic regression analysis. Its performance was analyzed using calibration-in-the-large, the slope of the calibration plot, concordance statistic (c-statistic), and the sensitivity and specificity of the training set, subsets, and a new test set.ResultsThe risk factors of CRE acquisition among ICU patients at a secondary referral hospital were Acute Physiology and Chronic Health Evaluation?II score at the time of admission, use of a central venous catheter and a nasogastric tube, as well as use of cephalosporin antibiotics. At 20.0% of the predicted CRE acquisition risk in the training set, the calibration-in-the-large was 0, slope of the calibration plot was 1, c-statistic was .93, sensitivity was 85.5%, and specificity was 84.8%. The performance was relatively good in the subsets and new test set.ConclusionThe nomogram can be used to monitor the CRE acquisition risk for ICU patients who have a similar case mix to patients in the study hospitals. Future studies need to involve more rigorous methodology and larger samples.
机译:目的研究旨在确定Carbapenem-Crestantentobacteriaceae(CRE)收购的危险因素,以建立CRE收购风险预测和评估其表现的罗布纳图。方法包括352名成年患者(55名患者和297名控股)承认2018年1月1日至2019年1月1日至2019年9月31日,在韩国釜山之间的453床二级推荐医院的重症监护室(ICU)。使用多个逻辑回归分析的识别风险因素建立了铭文图。使用校准绘图的斜率,校准统计(C统计)和训练集,子集和新测试集的敏感度和特异性来分析其性能。危险因素中学患者的ICU患者在急性生理学和慢性健康评估中获取急性生理学和慢性健康评估,在入院时分数,使用中央静脉导管和鼻咽管,以及头孢菌素抗生素的使用。在训练集中预测的CRE采集风险的20.0%,校准的大小为0,校准图的斜率为1,C统计为0.93,敏感性为85.5%,特异性为84.8% 。在子集和新测试集中的性能相对较好。结论该墨顶图可用于监测对研究医院患者具有类似案例混合的ICU患者的CRE采集风险。未来的研究需要涉及更严格的方法和更大的样品。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号