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首页> 美国卫生研究院文献>Materials >Evaluation of Antimicrobial Efficacy and Permeability of Various Sealing Materials at the Implant–Abutment Interface—A Pilot In Vitro Study
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Evaluation of Antimicrobial Efficacy and Permeability of Various Sealing Materials at the Implant–Abutment Interface—A Pilot In Vitro Study

机译：在植入式界面 - 植入界面的抗微生物功效和渗透性评价 - 植入式界面 - 一种在体外研究中的试验

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摘要

The microenvironment of the oral cavity is altered when an implant, a biocompatible foreign body, is inserted into the mouth. Bacteria settle in the tissues in and around the implant due to the passage of microorganisms through the microgap at the connection of the implant and prosthetic abutment. To prevent colonization of the implant by microorganisms, one idea is to use sealing and antimicrobial materials to decontaminate the implant–abutment interface and close the microgap. The purpose of this study is to evaluate the antimicrobial efficacy and permeability of different types of sealing materials at the implant–abutment interface, under static conditions. Three different sealing material (GapSeal gel, Oxysafe gel and Flow.sil) were used for sealing the implant–abutment interfaces in 60 titanium dental implants, which were first contaminated with a solution containing Staphylococcus aureus and Candida albicans for 14 days under an aerobic condition. Results showed that a complete seal against bacterial infection was not formed at the implant–abutment interface, while for fungal infections, only GapSeal material helped to prevent microleakage. Findings of this in vitro study reported that application of sealing material before abutment connection may reduce peri-implant bacterial and fungal population compared with the interface without sealing material.
机译：当植入物（生物相容性异物插入口中时，口腔的微环境被改变。由于在植入物和假脱机的连接，通过微生物通过微胶质通过微生物通过微生物的通过，细菌在植入物中沉淀。为了防止通过微生物定植植入物，一个思想是使用密封和抗微生物材料来消除植入邻接界面并关闭微涂层。本研究的目的是在静态条件下评估不同类型密封材料的抗微生物功效和渗透性。使用三种不同的密封材料（岩浆凝胶，oxysafe凝胶和流量）来密封60个钛牙科植入物中的植入邻接界面，其首先用含有葡萄球菌和念珠菌和念珠菌的溶液污染在有氧病症下14天。结果表明，在植入邻接界面上未形成对细菌感染的完全密封，而用于真菌感染，仅有助于防止微渗透。这种体外研究的结果报道说，与没有密封材料的界面相比，在邻接连接之前的施加在邻接连接前的施加可以减少Peri植入细菌和真菌群体。

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