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Hypersensitivity reactions due to black henna tattoos and their components: are the clinical pictures related to the immune pathomechanism?

机译:黑色指甲花纹身及其成分引起的超敏反应:临床表现与免疫机制有关吗?

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摘要

Hypersensitivity to para-phenylenediamine (PPD) and related compounds induced by temporary black henna tattoos has become a serious health problem worldwide. Different patterns of sensitization with various clinical aspects are described in literature due to PPD associated to henna tattoo and these manifestations are likely correlated with the immunological and dermatological pathomechanisms involved. Henna is the Persian name of the plant Lawsonia inermis, Fam. Lythraceae. It is a woody shrub that grow in regions of North Africa, South Asia, India and Sri Lanka. Nowadays it is rather frequent to see temporary “tattoos” performed with henna. To make tattoos darker and long-lasting PPD has been associated to henna in tattoo drawings mixtures, so obtaining “black henna”. In these years there has been a rise of contact sensitization to PPD and in medical literature an increased number of cases have been reported on temporary henna tattoo application. Here we review the various clinical patterns related to PPD and henna tattoo, to investigate the possible link between clinic-morphological pictures and the immunological response to PPD and henna. The literature underlines that different clinical manifestations are related to black henna containing PPD, and its derivative products may cause delayed-type as well as immediate-type reactions. Further studies are needed to investigate the relationship between clinical and morphological aspects of PPD contact dermatitis and the T cell subsets predominance.
机译:由暂时性的黑色指甲花纹身引起的对苯二胺(PPD)和相关化合物的超敏性已成为世界范围内的严重健康问题。由于与指甲花纹身有关的PPD,文献中描述了各种临床方面的不同敏化模式,这些表现很可能与所涉及的免疫学和皮肤病学机制有关。指甲花(Henna)是植物Lawsonia inermis,Fam的波斯语名称。千屈菜科。它是一种木本灌木,生长在北非,南亚,印度和斯里兰卡等地区。如今,看到指甲花临时染“纹身”已经相当普遍了。为使纹身更暗,持久,PPD已与纹身图纸混合物中的指甲花相关联,因此获得“黑色指甲花”。近年来,人们对PPD的接触敏锐度不断提高,在医学文献中,有关临时使用指甲花纹身的报道也有所增加。在这里,我们审查与PPD和指甲花纹身有关的各种临床模式,以调查临床形态图片与对PPD和指甲花的免疫反应之间的可能联系。文献强调不同的临床表现与含有PPD的黑色指甲花有关,其衍生产物可能引起迟发型和速发型反应。需要进一步研究以研究PPD接触性皮炎的临床和形态学方面与T细胞亚群优势之间的关系。

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