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首页> 美国卫生研究院文献>Clinical and Molecular Allergy : CMA >High frequency of IgE sensitization towards kiwi seed storage proteins among peanut allergic individuals also reporting allergy to kiwi
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High frequency of IgE sensitization towards kiwi seed storage proteins among peanut allergic individuals also reporting allergy to kiwi

机译：花生过敏者中对猕猴桃种子贮藏蛋白的IgE致敏频率较高也报告对猕猴桃过敏

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摘要

BackgroundIgE sensitization to storage proteins from nuts and seed is often related to severe allergic symptoms. There is a risk of immunological IgE cross-reactivity between storage proteins from different species. The potential clinical implication of such cross-reactivity is that allergens other than the known sensitizer can cause allergic symptoms. Previous studies have suggested that kiwi seed storage proteins may constitute hidden food allergens causing cross-reactive IgE-binding with peanut and other tree nut homologs, thereby mediating a potential risk of causing allergy symptoms among peanut ant tree nut allergic individuals. The objective of this study was to investigate the degree of sensitization towards kiwi fruit seed storage proteins in a cohort of peanut allergic individuals.
机译：BackgroundIgE对坚果和种子中储存蛋白的致敏作用通常与严重的过敏症状有关。不同物种的存储蛋白之间存在免疫学IgE交叉反应的风险。这种交叉反应的潜在临床含义是，除已知的敏化剂外的其他过敏原都可能引起过敏症状。先前的研究表明，猕猴桃种子贮藏蛋白可能构成隐藏的食物过敏原，导致与花生和其他坚果同源物的交叉反应性IgE结合，从而在花生蚂蚁坚果过敏个体中介导引起过敏症状的潜在风险。这项研究的目的是研究一群花生过敏个体对猕猴桃种子贮藏蛋白的敏感性程度。

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