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首页> 美国卫生研究院文献>Clinical and Molecular Allergy : CMA >Burden of allergic respiratory disease: a systematic review
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Burden of allergic respiratory disease: a systematic review

机译：过敏性呼吸系统疾病的负担：系统评价

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This meta-analysis compared the health-related quality of life (HRQL) of patients with allergic rhinitis (AR) and/or allergic asthma (AA) caused by perennial house dust mite (HDM) versus AR and/or AA caused by seasonal pollen allergy. Following a systematic search, the identified studies used the disease-specific rhinitis quality of life questionnaire or generic instruments (SF-36 and SF-12). Summary estimates obtained by meta-analysis showed that HRQL in patients with perennial HDM allergy was significantly worse than that of patients with seasonal pollen allergy, when measured by both disease-specific and generic HRQL instruments, and was reflected by an impact on both physical and mental health. A systematic review of cost data on AR and AA in selected European countries demonstrated that the majority of the economic burden was indirectly caused by high levels of absenteeism and presenteeism; there was little or no evidence of increasing or decreasing cost trends. Increased awareness of the detrimental effects of AR and/or AA on patients’ HRQL and its considerable cost burden might encourage early diagnosis and treatment, in order to minimize the disease burden and ensure beneficial and cost-effective outcomes.Electronic supplementary materialThe online version of this article (doi:10.1186/s12948-016-0049-9) contains supplementary material, which is available to authorized users.
机译：这项荟萃分析比较了常年性室内尘螨（HDM）引起的过敏性鼻炎（AR）和/或过敏性哮喘（AA）患者与季节性花粉引起的AR和/或AA患者的健康相关生活质量（HRQL）过敏。经过系统搜索，确定的研究使用了针对疾病的鼻炎生活质量调查表或通用工具（SF-36和SF-12）。通过荟萃分析得出的摘要估计表明，通过疾病特异性和通用HRQL仪器进行测量，常年HDM过敏患者的HRQL明显比季节性花粉过敏患者的HRQL差，并且反映了对身体和身体的影响精神健康。对某些欧洲国家的AR和AA成本数据进行的系统审查显示，大部分经济负担是由旷工和出席者的高水平间接造成的；几乎没有或没有证据表明成本趋势会增加或减少。增强对AR和/或AA对患者HRQL的有害作用及其巨大成本负担的认识可能会鼓励早期诊断和治疗，以最大程度地减少疾病负担并确保有益和具有成本效益的结果。本文（doi：10.1186 / s12948-016-0049-9）包含补充材料，授权用户可以使用。

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