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Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

机译：几丁质酶3-like-1由人Th17细胞产生与青少年特发性关节炎患者的炎症水平相关

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BackgroundCHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but their production by human T cells, has never been reported.

机译：背景技术CHI3L1是一种无酶活性的几丁质酶样蛋白，由活化的巨噬细胞，软骨细胞，嗜中性粒细胞产生。关于关节炎，哮喘和炎性肠病的最新研究表明，几丁质酶在炎性过程和组织重塑中很重要，但从未报道过由人T细胞产生的几丁质酶。

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期刊名称 Clinical and Molecular Allergy : CMA
作者
Manuela Capone; Laura Maggi; Veronica Santarlasci; Maria Caterina Rossi; Alessio Mazzoni; Gianni Montaini; Rolando Cimaz; Matteo Ramazzotti; Marie Pierre Piccinni; Giusi Barra; Raffaele De Palma; Francesco Liotta; Enrico Maggi; Sergio Romagnani; Francesco Annunziato; Lorenzo Cosmi;
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年(卷),期 2016(14),-1
年度 2016
页码 16
总页数 9
原文格式 PDF
正文语种
中图分类分子生物学;
关键词
CHI3L1 Th17 cells CD161 SF JIA CRP;

机译：CHI3L1;Th17细胞;CD161;SF;JIA;CRP;

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1. Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients [J] . Manuela Capone, Laura Maggi, Veronica Santarlasci, Clinical and Molecular Allergy . 2016,第1期

机译：几丁质酶3-like-1由人Th17细胞产生，与青少年特发性关节炎患者的炎症水平相关
2. Persistent improper upregulation of Th17 and T-Reg cells in patients with juvenile idiopathic arthritis [J] . Wu Shun-An, Yeh Kuo-Wei, Lee Wen-I, Journal of microbiology, immunology, and infection: Wei mian yu gan ran za zhi . 2016,第3期

机译：幼年特发性关节炎患者中Th17和T-Reg细胞的持续不适当的上调
3. Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis [J] . Lorenzo Cosmi, Rolando Cimaz, Laura Maggi, Arthritis & Rheumatism . 2011,第8期

机译：幼年特发性关节炎患者滑液中CD4 + CD161 + T细胞Th17表型的瞬时性质的证据
4. Change Point Detection in Knee Acoustic Emissions using the Teager Operator: A Preliminary Study in Patients with Juvenile Idiopathic Arthritis [C] . Beren Semiz, Sinan Hersek, Daniel C. Whittingslow, IEEE EMBS International Conference on Biomedical Health Informatics . 2019

机译：使用Teager操作员检测膝盖声发射中的变化点：对青少年特发性关节炎患者的初步研究
5. 25-hydroxyvitamin D Levels and Juvenile Idiopathic Arthritis: Is there an Association with Disease Activity? [D] . Pelajo, Christina Feitosa. 2011

机译：25-羟基维生素D水平与青少年特发性关节炎：与疾病活动有关吗？
6. Soluble Receptor for Advanced Glycation End Products (sRAGE) is decreased in patients with Juvenile Idiopathic Arthritis (ERA category) and inversely correlates with disease activity and S100A12 levels [O] . Amita Aggarwal, Arpita Myles, Vishad Viswanath, 2011

机译：幼年特发性关节炎（ERA类）患者的晚期糖基化终产物（sRAGE）可溶性受体降低并且与疾病活性和S100A12水平成反比
7. Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients [O] . Manuela Capone, Laura Maggi, Veronica Santarlasci, 2016

机译：几丁质酶3-like-1由人Th17细胞产生，与青少年特发性关节炎患者的炎症水平相关

Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

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