Objectives:To investigate the clinical efficacy of Honghua Ruyi pill for endometriosis cause of secondary dysmenorrhea.Methods:106 patients were randomized to observe the major therapeutic index and sec-ondary indexes in patients on the treatment day 0,day 30,day 90,and the day 30,day 60,day 90 after stopping administration to compare the efficiency of Red Ruyi pill and Gestrinone in treating secondary dysmenorrheal caused by endometriosis.Results:The cure rate of the two drugs,during treatment and day 30 after stopping administra-tion,was of no significant difference (P>0.025).On the visit day 60 and day 90,the cure rate of Red Ruyi pill was significantly higher than that of Gestrinone,with significant difference (P<0.0001 ).Conclusion:Red Ruyi Pill is more effective than Gestrinone in the treatment of secondary dysmenorrheal caused by endometriosis.%目的：探讨红花如意丸对子宫内膜异位症导致的继发性痛经的临床疗效。方法：将106例患者随机分组，分别在用药第0d、30d、60d、90d和停药第30d、60d、90d对患者的主要治疗指标和次要治疗指标进行观察测量，对比观察红花如意丸与孕三烯酮治疗子宫内膜异位症导致的继发性痛经的临床疗效。结果：用药期间及停药第30天时两药治愈率无明显差异（P＞0．025），访视60d及90d时，红花如意丸治愈率明显高于孕三烯酮组，差别有显著性意义（P＜0．0001）。结论：红花如意丸治疗子宫内膜异位症继发痛经的疗效优于孕三烯酮。
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