A New Triterpenoid Saponin and Two Neolignans from Ligularia veitchiana

机译：一个新的三萜皂苷和两个来自Li草的新木脂素。

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Phytochemical investigation of the rhizomes and roots of Ligularia veitchiana afforded a new triterpenoid saponin and two known neolignans named liguveitoside B (1), citrusin A (2) and cit-rusin B (3), respectively. This is the first demonstration of the occurrence of a 8-O-4' neolignan and the second report on the isolation of triterpenoid saponin in the genus Ligularia. Their structures were elucidated on the basis of spectral data, particularly HSQC, HMBC and NOE experiments. Compound 1 exhibited weak cytotoxicity against a human acute promyelocytic leukemia cell-line (HL-60).

机译：植物学研究的Ligularia veitchiana的根茎和根提供了一个新的三萜皂苷和两个已知的新木脂素，分别称为liguveitoside B（1），柑桔素A（2）和柑桔素B（3）。这是8-O-4'neolignan发生的第一个证明，也是关于Ligularia属中三萜皂苷的分离的第二份报道。根据光谱数据，特别是HSQC，HMBC和NOE实验，阐明了它们的结构。化合物1对人急性早幼粒细胞白血病细胞系（HL-60）显示出弱的细胞毒性。

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来源
《Collection of Academic Papers(2004)》||P.184-187|共4页
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作者
Hui Zhu; Pengfei Tu;
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作者单位

School of Pharmaceutical Sciences, Peking University, Health Science Center, 38 Xueyuan Road, Beijing, 100083, P. R. China;

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原文格式 PDF
正文语种 eng
中图分类中医基础理论;中药学;
关键词
ligularia veitchiana; liguveitoside B; neolignan; saponin;

机译：药;甜菜苷B;新木脂素;皂苷;

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1. A new triterpenoid saponin and two neolignans from Ligularia veitchiana [J] . Zhu H, Tu PF Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences . 2004,第9期

机译：一个新的三萜皂苷和两个来自淡水百合的新木脂素
2. New triterpenoid saponins with cytotoxic activities from Ligularia przewalskii [J] . Shi Zhuan-Ning, Wang Yu-Dong, Gong Yuan, Phytochemistry Letters . 2019,第期

机译：新的三萜类皂苷，来自Ligularia przewalskii的细胞毒性活动
3. New Triterpenoid Saponins and Neolignans from Morina kokonorica [J] . Ying Zhu, Zhang-Ping Lu, Cai-Bin Xue, Helvetica chimica acta . 2009,第3期

机译：Morina kokonorica的新三萜皂苷和新木脂素
4. Structure Elucidation of Two Triterpenoid Saponins from Leaves of Schima superba Gardn. et Champ [C] . Guanghua Huo, Changling Zhang, Yingjun Zhang International conference on applied biotechnology . 2014

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5. Isolation, characterization and estimation of some triterpenoid saponins and its aglycones from Indian medicinal plants. [D] . Ezhava, Sindhu B. 2009

机译：印度药用植物中三萜类皂苷及其苷元的分离，鉴定和评估。
6. New dammarane-type triterpenoid saponins from Panax notoginseng saponins [O] . Qian Li, Mingrui Yuan, Xiaohui Li, 2020

机译：来自Panax Notoginseng Saponins的新Dammarane型三萜皂苷
7. An examination of the Rubiaceae of Rong Kong. VII. The occurrence of triterpenoids, steroids, and triterpenoid saponins [O] . WH Hui, CT Ho 1968

机译：对荣王茜草科检查。 VII。三萜类化合物，类固醇和三萜类皂苷的发生

A New Triterpenoid Saponin and Two Neolignans from Ligularia veitchiana

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